Scleroderma

Scleroderma is an autoimmune disorder whose hallmark is increased collagen deposition and hardening of the skin.

While research continues to evolve our understanding of this disease, the main feature is abnormal function of fibroblast cells leading to the increased collagen deposition.

The increased deposition can lead to changes in the skin, kidneys, gastrointestinal tract, and other areas.  This family of diseases often shares clinical features with inflammatory muscle diseases, mixed connective tissue disease (MCTD), rheumatoid arthritis, and Sjogren’s syndrome.  Many different organ systems can become involved including the pulmonary and cardiac systems.

The classically described forms are diffuse cutaneous systemic sclerosis (common referred to as “scleroderma”), and limited cutaneous systemic sclerosis (commonly referred to as CREST syndrome- Calcinosis, Raynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasias).  Diffuse cutaneous systemic sclerosis tends to involve more proximal skin changes, and can be associated with interstitial lung disease.  Limited cutaneous systemic sclerosis generally shows more distal skin changes, can involve the problems listed in the letters “CREST”, and can be associated with primary pulmonary hypertension.

Scleroderma related disorders can be quite severe.  However, with appropriate recognition and diagnosis, many of the problems can be anticipated and/or managed.  There are newer approaches to treat the most severe forms of disease including interstitial lung disease and primary pulmonary hypertension.  These problems are often co-managed with pulmonary physicians and cardiologists.

Oct 11, 2017

Live Well: How to Support your Partner after an Arthritis Diagnosis

healthy-living-tips-how-to-support-your-partner-after-arthritis-diagnosis

The best medicine after receiving an arthritis diagnosis can be a strong and healthy relationship’s support. Studies show that arthritis patients in a contented relationship had less pain and psychological disability. So how can you support your companion and keep your partnership strong? Try these tips to help improve a struggling relationship, or further strengthen […]

Read More »

Sep 21, 2017

Live Well: 7 Tips That Will Keep you Gardening

healthy-living-tips-continuing-favorite-outdoor-activities-with-arthritis

Stress relief, sunshine, a sense of accomplishment, fresh air—these are just some of the many benefits from gardening. Unfortunately, if you suffer from arthritis, your favorite hobby can become your worst enemy. Simply carrying essential tools or moving between beds can be a challenge. Don’t let arthritis pain force you to give up your green […]

Read More »

Sep 15, 2017

Introducing Dr. Daniel DeLo

introducing-dr-daniel-delo-carolina-arthritis-physician

Carolina Arthritis is extremely excited to welcome Dr. Daniel DeLo to our team. Dr. DeLo was raised in Morgantown, West Virginia and received his undergraduate and medical degrees from West Virginia University. He’s comfortable treating a wide variety of rheumatology issues, but has a special interest in autoimmune diseases such as gout, rheumatoid arthritis, psoriatic […]

Read More »